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β-sitosterol ameliorates influenza A virus-induced proinflammatory response and acute lung injury in mice by disrupting the cross-talk between RIG-I and IFN/STAT signaling

β-Sitosterol (24-ethyl-5-cholestene-3-ol) is a common phytosterol Chinese medical plants that has been shown to possess antioxidant and anti-inflammatory activity. In this study we investigated the effects of β-sitosterol on influenza virus-induced inflammation and acute lung injury and the molecula...

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Detalles Bibliográficos
Autores principales: Zhou, Bei-xian, Li, Jing, Liang, Xiao-li, Pan, Xi-ping, Hao, Yan-bing, Xie, Pei-fang, Jiang, Hai-ming, Yang, Zi-feng, Zhong, Nan-shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273125/
https://www.ncbi.nlm.nih.gov/pubmed/32504068
http://dx.doi.org/10.1038/s41401-020-0403-9