New PAR1 Agonist Peptide Demonstrates Protective Action in a Mouse Model of Photothrombosis-Induced Brain Ischemia

Protease-activated receptors (PARs) are involved not only in hemostasis but also in the development of ischemic brain injury. In the present work, we examined in vivo effects of a new peptide (AP9) composing Asn(47)-Phen(55) of PAR1 “tethered ligand” generated by activated protein C. We chose a mous...

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Detalles Bibliográficos
Autores principales: Galkov, Maksim, Kiseleva, Ekaterina, Gulyaev, Mikhail, Sidorova, Maria, Gorbacheva, Liubov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273131/
https://www.ncbi.nlm.nih.gov/pubmed/32547356
http://dx.doi.org/10.3389/fnins.2020.00335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273131/
https://www.ncbi.nlm.nih.gov/pubmed/32547356
http://dx.doi.org/10.3389/fnins.2020.00335

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