Characterizing the Causal Pathway for Genetic Variants Associated with Neurological Phenotypes Using Human Brain-Derived Proteome Data

Leveraging high-dimensional molecular datasets can help us develop mechanistic insight into associations between genetic variants and complex traits. In this study, we integrated human proteome data derived from brain tissue to evaluate whether targeted proteins putatively mediate the effects of gen...

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Detalles Bibliográficos
Autores principales: Kibinge, Nelson K., Relton, Caroline L., Gaunt, Tom R., Richardson, Tom G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273531/
https://www.ncbi.nlm.nih.gov/pubmed/32413284
http://dx.doi.org/10.1016/j.ajhg.2020.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273531/
https://www.ncbi.nlm.nih.gov/pubmed/32413284
http://dx.doi.org/10.1016/j.ajhg.2020.04.007

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