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Epigenome-wide association study in healthy individuals identifies significant associations with DNA methylation and PBMC extract VEGF-A concentration

INTRODUCTION: Vascular endothelial growth factor A (VEGF-A) is a chemokine that induces proliferation and migration of vascular endothelial cells and is essential for both physiological and pathological angiogenesis. It is known for its high heritability (> 60%) and involvement in most common mor...

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Detalles Bibliográficos
Autores principales: Gorenjak, Vesna, Vance, Dwaine R., Dade, Sébastien, Stathopoulou, Maria G., Doherty, Lauren, Xie, Ting, Murray, Helena, Masson, Christine, Lamont, John, Fitzgerald, Peter, Visvikis-Siest, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273671/
https://www.ncbi.nlm.nih.gov/pubmed/32503626
http://dx.doi.org/10.1186/s13148-020-00874-w