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Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells

BACKGROUND: Understanding the signalling pathways involved in angiogenesis, and developing anti-angiogenic drugs are one of the major focuses on cancer research. Herein, we assessed the effect of CPTH6, a lysine acetyltransferase inhibitor and anti-tumoral compound, on angiogenesis-related propertie...

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Detalles Bibliográficos
Autores principales: Di Martile, Marta, Gabellini, Chiara, Desideri, Marianna, Matraxia, Marta, Farini, Valentina, Valentini, Elisabetta, Carradori, Simone, Ercolani, Cristiana, Buglioni, Simonetta, Secci, Daniela, Andreazzoli, Massimiliano, Del Bufalo, Donatella, Trisciuoglio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273677/
https://www.ncbi.nlm.nih.gov/pubmed/32498717
http://dx.doi.org/10.1186/s13046-020-01604-z