Protection From Influenza by Intramuscular Gene Vector Delivery of a Broadly Neutralizing Nanobody Does Not Depend on Antibody Dependent Cellular Cytotoxicity

Cross-subtype neutralizing single domain antibodies against influenza present new opportunities for immunoprophylaxis and pandemic preparedness. Their simple modular structure and single open reading frame format are highly amenable to gene therapy-mediated delivery. We have previously described R1a...

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Detalles Bibliográficos
Autores principales: Del Rosario, Joanne Marie M., Smith, Matthew, Zaki, Kam, Risley, Paul, Temperton, Nigel, Engelhardt, Othmar G., Collins, Mary, Takeuchi, Yasuhiro, Hufton, Simon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273724/
https://www.ncbi.nlm.nih.gov/pubmed/32547534
http://dx.doi.org/10.3389/fimmu.2020.00627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273724/
https://www.ncbi.nlm.nih.gov/pubmed/32547534
http://dx.doi.org/10.3389/fimmu.2020.00627

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