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Insights From Computational Modeling Into the Contribution of Mechano-Calcium Feedback on the Cardiac End-Systolic Force-Length Relationship

In experimental studies on cardiac tissue, the end-systolic force-length relation (ESFLR) has been shown to depend on the mode of contraction: isometric or isotonic. The isometric ESFLR is derived from isometric contractions spanning a range of muscle lengths while the isotonic ESFLR is derived from...

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Detalles Bibliográficos
Autores principales: Guidry, Megan E., Nickerson, David P., Crampin, Edmund J., Nash, Martyn P., Loiselle, Denis S., Tran, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273927/
https://www.ncbi.nlm.nih.gov/pubmed/32547426
http://dx.doi.org/10.3389/fphys.2020.00587