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Crystal structure of a 1:1 co-crystal of the anticancer drug gefitinib with azelaic acid
In the title co-crystal, C(22)H(24)ClFN(4)O(3)·C(9)H(16)O(4), gefitinib (GTB; systematic name: quinazolin-4-amine) co-crystallizes with azelaic acid (AA; systematic name: nonanedioic acid). The co-crystal has the monoclinic P2(1)/n centrosymmetric space group, containing one molecule each of GTB a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274001/ https://www.ncbi.nlm.nih.gov/pubmed/32523757 http://dx.doi.org/10.1107/S2056989020006623 |