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Crystal structure of a 1:1 co-crystal of the anti­cancer drug gefitinib with azelaic acid

In the title co-crystal, C(22)H(24)ClFN(4)O(3)·C(9)H(16)O(4), gefitinib (GTB; systematic name: quinazolin-4-amine) co-crystallizes with azelaic acid (AA; systematic name: nona­nedioic acid). The co-crystal has the monoclinic P2(1)/n centrosymmetric space group, containing one mol­ecule each of GTB a...

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Detalles Bibliográficos
Autores principales: George, Christy P., Sangtani, Ekta, Gonnade, Rajesh G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274001/
https://www.ncbi.nlm.nih.gov/pubmed/32523757
http://dx.doi.org/10.1107/S2056989020006623