In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

Computational chemistry has now been widely accepted as a useful tool for shortening lead times in early drug discovery. When selecting new potential drug targets, it is important to assess the likelihood of finding suitable starting points for lead generation before pursuing costly high-throughput...

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Detalles Bibliográficos
Autores principales: Michel, Maurice, Homan, Evert J., Wiita, Elisée, Pedersen, Kia, Almlöf, Ingrid, Gustavsson, Anna-Lena, Lundbäck, Thomas, Helleday, Thomas, Warpman Berglund, Ulrika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274155/
https://www.ncbi.nlm.nih.gov/pubmed/32548091
http://dx.doi.org/10.3389/fchem.2020.00443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274155/
https://www.ncbi.nlm.nih.gov/pubmed/32548091
http://dx.doi.org/10.3389/fchem.2020.00443

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