Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells

Generation of pancreatic β cells from human pluripotent stem cells (hPSCs) holds promise as a cell replacement therapy for diabetes. Here, we establish a link between the state of the actin cytoskeleton and the expression of pancreatic transcription factors that drive pancreatic lineage specificatio...

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Detalles Bibliográficos
Autores principales: Hogrebe, Nathaniel J., Augsornworawat, Punn, Maxwell, Kristina G., Velazco-Cruz, Leonardo, Millman, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274216/
https://www.ncbi.nlm.nih.gov/pubmed/32094658
http://dx.doi.org/10.1038/s41587-020-0430-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274216/
https://www.ncbi.nlm.nih.gov/pubmed/32094658
http://dx.doi.org/10.1038/s41587-020-0430-6

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