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Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity

Growth Differentiation Factor-15 (GDF15) is a divergent TGF-beta superfamily cytokine that is overexpressed by most cancers and is induced by anticancer therapy. Transgenic and induced animal models suggest that it protects from cancer development but the mechanisms are uncertain. We investigated th...

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Detalles Bibliográficos
Autores principales: Husaini, Yasmin, Tsai, Vicky Wang-Wei, Manandhar, Rakesh, Zhang, Hong Ping, Lee-Ng, Ka Ki Michelle, Lebhar, Hélène, Marquis, Christopher P., Brown, David A., Breit, Samuel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274405/
https://www.ncbi.nlm.nih.gov/pubmed/32502202
http://dx.doi.org/10.1371/journal.pone.0233846