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A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank

Psychiatric disorders are highly heritable and associated with a wide variety of social adversity and physical health problems. Using genetic liability (rather than phenotypic measures of disease) as a proxy for psychiatric disease risk can be a useful alternative for research questions that would t...

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Detalles Bibliográficos
Autores principales: Leppert, Beate, Millard, Louise A. C., Riglin, Lucy, Davey Smith, George, Thapar, Anita, Tilling, Kate, Walton, Esther, Stergiakouli, Evie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274459/
https://www.ncbi.nlm.nih.gov/pubmed/32392212
http://dx.doi.org/10.1371/journal.pgen.1008185