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Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation

The biconcave disk shape of the mammalian red blood cell (RBC) is unique to the RBC and is vital for its circulatory function. Due to the absence of a transcellular cytoskeleton, RBC shape is determined by the membrane skeleton, a network of actin filaments cross-linked by spectrin and attached to m...

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Detalles Bibliográficos
Autores principales: Alimohamadi, Haleh, Smith, Alyson S., Nowak, Roberta B., Fowler, Velia M., Rangamani, Padmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274484/
https://www.ncbi.nlm.nih.gov/pubmed/32453720
http://dx.doi.org/10.1371/journal.pcbi.1007890