The selective glucocorticoid receptor antagonist CORT125281 has tissue-specific activity

Glucocorticoids mediate numerous essential processes in the human body via binding to the glucocorticoid receptor (GR). Excessive GR signaling can cause disease, and GR antagonists can be used to treat many symptoms of glucocorticoid-induced pathology. The purpose of this study was to characterize t...

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Detalles Bibliográficos
Autores principales: Koorneef, Lisa L, Kroon, Jan, Viho, Eva M G, Wahl, Lucas F, Heckmans, Kim M L, van Dorst, Marloes M A R, Hoekstra, Menno, Houtman, René, Hunt, Hazel, Meijer, Onno C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274539/
https://www.ncbi.nlm.nih.gov/pubmed/32369774
http://dx.doi.org/10.1530/JOE-19-0486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274539/
https://www.ncbi.nlm.nih.gov/pubmed/32369774
http://dx.doi.org/10.1530/JOE-19-0486

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