Estrogen induces dynamic ERα and RING1B recruitment to control gene and enhancer activities in luminal breast cancer

RING1B, a core Polycomb repressive complex 1 subunit, is a histone H2A ubiquitin ligase essential for development. RING1B is overexpressed in patients with luminal breast cancer (BC) and recruited to actively transcribed genes and enhancers co-occupied by the estrogen receptor α (ERα). Whether ERα-i...

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Detalles Bibliográficos
Autores principales: Zhang, Yusheng, Chan, Ho Lam, Garcia-Martinez, Liliana, Karl, Daniel L., Weich, Natalia, Slingerland, Joyce M., Verdun, Ramiro E., Morey, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274770/
https://www.ncbi.nlm.nih.gov/pubmed/32548262
http://dx.doi.org/10.1126/sciadv.aaz7249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274770/
https://www.ncbi.nlm.nih.gov/pubmed/32548262
http://dx.doi.org/10.1126/sciadv.aaz7249

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