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β-arrestin-1 suppresses myogenic reprogramming of brown fat to maintain euglycemia

A better understanding of the signaling pathways regulating adipocyte function is required for the development of new classes of antidiabetic/obesity drugs. We here report that mice lacking β-arrestin-1 (barr1), a cytoplasmic and nuclear signaling protein, selectively in adipocytes showed greatly im...

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Detalles Bibliográficos
Autores principales: Pydi, Sai P., Jain, Shanu, Barella, Luiz F., Zhu, Lu, Sakamoto, Wataru, Meister, Jaroslawna, Wang, Lei, Lu, Huiyan, Cui, Yinghong, Gavrilova, Oksana, Wess, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274797/
https://www.ncbi.nlm.nih.gov/pubmed/32548266
http://dx.doi.org/10.1126/sciadv.aba1733