In silico models for evaluating proarrhythmic risk of drugs

Safety evaluation of drugs requires examination of the risk of generating Torsade de Pointes (TdP) because it can lead to sudden cardiac death. Until recently, the QT interval in the electrocardiogram (ECG) has been used in the evaluation of TdP risk because the QT interval is known to be associated...

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Detalles Bibliográficos
Autores principales: Hwang, Minki, Lim, Chul-Hyun, Leem, Chae Hun, Shim, Eun Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274812/
https://www.ncbi.nlm.nih.gov/pubmed/32548538
http://dx.doi.org/10.1063/1.5132618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274812/
https://www.ncbi.nlm.nih.gov/pubmed/32548538
http://dx.doi.org/10.1063/1.5132618

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