Randomized controlled trial of N-acetylcysteine therapy for RYR1-related myopathies

OBJECTIVE: To investigate the efficacy of N-acetylcysteine (NAC) for decreasing elevated oxidative stress and increasing physical endurance in individuals with ryanodine receptor 1-related myopathies (RYR1-RM). METHODS: In this 6-month natural history assessment (n = 37) followed by a randomized, do...

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Detalles Bibliográficos
Autores principales: Todd, Joshua J., Lawal, Tokunbor A., Witherspoon, Jessica W., Chrismer, Irene C., Razaqyar, Muslima S., Punjabi, Monal, Elliott, Jeffrey S., Tounkara, Fatoumata, Kuo, Anna, Shelton, Monique O., Allen, Carolyn, Cosgrove, Mary M., Linton, Melody, Michael, Darren, Jain, Minal S., Waite, Melissa, Drinkard, Bart, Wakim, Paul G., Dowling, James J., Bönnemann, Carsten G., Emile-Backer, Magalie, Meilleur, Katherine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Null Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274912/
https://www.ncbi.nlm.nih.gov/pubmed/31941795
http://dx.doi.org/10.1212/WNL.0000000000008872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274912/
https://www.ncbi.nlm.nih.gov/pubmed/31941795
http://dx.doi.org/10.1212/WNL.0000000000008872

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