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MRI vastus lateralis fat fraction predicts loss of ambulation in Duchenne muscular dystrophy

OBJECTIVE: We studied the potential of quantitative MRI (qMRI) as a surrogate endpoint in Duchenne muscular dystrophy by assessing the additive predictive value of vastus lateralis (VL) fat fraction (FF) to age on loss of ambulation (LoA). METHODS: VL FFs were determined on longitudinal Dixon MRI sc...

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Detalles Bibliográficos
Autores principales: Naarding, Karin J., Reyngoudt, Harmen, van Zwet, Erik W., Hooijmans, Melissa T., Tian, Cuixia, Rybalsky, Irina, Shellenbarger, Karen C., Le Louër, Julien, Wong, Brenda L., Carlier, Pierre G., Kan, Hermien E., Niks, Erik H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274919/
https://www.ncbi.nlm.nih.gov/pubmed/31937624
http://dx.doi.org/10.1212/WNL.0000000000008939