Evolution and function of interleukin-4 receptor signaling in adaptive immunity and neutrophils

The cytokines interleukin (IL)-4 and IL-13, signaling via the IL-4 receptor (IL-4R), orchestrate type 2 immunity to helminth infections and toxins. Activation of epithelial and myeloid cells, and a transient neutrophils influx initiates type 2 immune responses, which are dominated by basophils, eosi...

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Detalles Bibliográficos
Autores principales: Heeb, Lukas E. M., Egholm, Cecilie, Boyman, Onur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274943/
https://www.ncbi.nlm.nih.gov/pubmed/32139893
http://dx.doi.org/10.1038/s41435-020-0095-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274943/
https://www.ncbi.nlm.nih.gov/pubmed/32139893
http://dx.doi.org/10.1038/s41435-020-0095-7

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