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Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat

Similar to humans, the risk of cerebrovascular disease in stroke-prone spontaneously hypertensive rats (SHR-A3/SHRSP) arises from naturally occurring genetic variation. In the present study, we show the involvement of genetic variation affecting the store-operated calcium signaling gene, Stim1, in t...

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Detalles Bibliográficos
Autores principales: Dhande, Isha S., Kneedler, Sterling C., Zhu, Yaming, Joshi, Aniket S., Hicks, M. John, Wenderfer, Scott E., Braun, Michael C., Doris, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274944/
https://www.ncbi.nlm.nih.gov/pubmed/32300198
http://dx.doi.org/10.1038/s41435-020-0097-5