Cargando…

Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat

Similar to humans, the risk of cerebrovascular disease in stroke-prone spontaneously hypertensive rats (SHR-A3/SHRSP) arises from naturally occurring genetic variation. In the present study, we show the involvement of genetic variation affecting the store-operated calcium signaling gene, Stim1, in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dhande, Isha S., Kneedler, Sterling C., Zhu, Yaming, Joshi, Aniket S., Hicks, M. John, Wenderfer, Scott E., Braun, Michael C., Doris, Peter A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274944/ https://www.ncbi.nlm.nih.gov/pubmed/32300198 http://dx.doi.org/10.1038/s41435-020-0097-5

Ejemplares similares

Stim1 Polymorphism Disrupts Immune Signaling and Creates Renal Injury in Hypertension
por: Dhande, Isha S., et al.
Publicado: (2020)

Identification of Stim1 as a Candidate Gene for Exaggerated Sympathetic Response to Stress in the Stroke-Prone Spontaneously Hypertensive Rat
por: Ferdaus, Mohammed Zubaerul, et al.
Publicado: (2014)

Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
por: Li, Xin, et al.
Publicado: (2017)

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines
por: Zheng, Sisi, et al.
Publicado: (2018)

Sacral neuromodulation for overactive bladder using the InterStim and BetterStim systems
por: Meng, Lingfeng, et al.
Publicado: (2022)

Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation
por: Sogkas, Georgios, et al.
Publicado: (2015)

STIM1 strengthens clotting
por: Bashyam, Hema
Publicado: (2008)

The regulation of STIM1 by phosphorylation
por: Pozo-Guisado, Eulalia, et al.
Publicado: (2013)

Role of STIM1 in neurodegeneration
por: Pascual-Caro, Carlos, et al.
Publicado: (2018)

The many states of STIM1
por: Fahrner, Marc, et al.
Publicado: (2021)

Stim-activated TRPC-ORAI channels in pulmonary hypertension induced by chronic intermittent hypoxia
por: Castillo-Galán, Sebastian, et al.
Publicado: (2020)

Differential Roles for STIM1 and STIM2 in Store-Operated Calcium Entry in Rat Neurons
por: Gruszczynska-Biegala, Joanna, et al.
Publicado: (2011)

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia
por: Fleur-Lominy, Shella Saint, et al.
Publicado: (2018)

ATP depletion induces translocation of STIM1 to puncta and formation of STIM1–ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP
por: Chvanov, Michael, et al.
Publicado: (2008)

The Drosophila STIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning
por: Eid, Jean-Pierre, et al.
Publicado: (2008)

Calcium Sensors STIM1 and STIM2 Regulate Different Calcium Functions in Cultured Hippocampal Neurons
por: Kushnireva, Liliya, et al.
Publicado: (2021)

The role of plasma membrane STIM1 and Ca(2 +)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets
por: Ambily, A., et al.
Publicado: (2014)

The Ca(2+) Sensor STIM in Human Diseases
por: Berna-Erro, Alejandro, et al.
Publicado: (2023)

Orais and STIMs: physiological mechanisms and disease
por: Berna-Erro, A, et al.
Publicado: (2012)

The STIM1/Orai signaling machinery
por: Fahrner, Marc, et al.
Publicado: (2013)

Molecular mechanisms of STIM/Orai communication
por: Derler, Isabella, et al.
Publicado: (2016)

STIM and ORAI proteins in the nervous system
por: Kraft, Robert
Publicado: (2015)

The role of STIM proteins in neutrophil functions
por: Demaurex, Nicolas, et al.
Publicado: (2018)

STIM Proteins: An Ever-Expanding Family
por: Grabmayr, Herwig, et al.
Publicado: (2020)

STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells
por: Weidinger, Carl, et al.
Publicado: (2013)

A cholesterol-binding domain in STIM1 modulates STIM1-Orai1 physical and functional interactions
por: Pacheco, Jonathan, et al.
Publicado: (2016)

Differential role of STIM1 and STIM2 during transient inward (T(in)) current generation and the maturation process in the Xenopus oocyte
por: Serrano-Flores, Barbara, et al.
Publicado: (2014)

STIM1 Phosphorylation at Y361 Recruits Orai1 to STIM1 Puncta and Induces Ca(2+) Entry
por: Yazbeck, Pascal, et al.
Publicado: (2017)

S417 in the CC3 region of STIM1 is critical for STIM1-Orai1 binding and CRAC channel activation
por: Yu, Tao, et al.
Publicado: (2023)

A new approach to identifying hypertension-associated genes in the mesenteric artery of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats
por: Ikawa, Takashi, et al.
Publicado: (2019)

In this issue of Channels: Special issue on STIM and Orai
por: Romanin, Christoph
Publicado: (2013)

Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin converting enzyme-2/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury
por: Ali, Quaisar, et al.
Publicado: (2016)

Deficient for endoplasmic reticulum calcium sensors Stim1 and Stim2 affects aberrant antibody affinity maturation in B cells
por: Mao, Xuhua, et al.
Publicado: (2016)

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction
por: Varga-Szabo, David, et al.
Publicado: (2008)

Interleukin-1β Accelerates the Onset of Stroke in Stroke-Prone Spontaneously Hypertensive Rats
por: Chiba, Tsuyoshi, et al.
Publicado: (2012)

Hemolytic uremic syndrome as the presenting manifestation of WT1 mutation and Denys-Drash syndrome: a case report
por: Alge, Joseph L., et al.
Publicado: (2017)

Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP(3) Receptors
por: Lur, Gyorgy, et al.
Publicado: (2009)

Oligomerization and Ca(2+)/calmodulin control binding of the ER Ca(2+)-sensors STIM1 and STIM2 to plasma membrane lipids
por: Bhardwaj, Rajesh, et al.
Publicado: (2013)

STIM1 Knockout Enhances PDGF-Mediated Ca(2+) Signaling through Upregulation of the PDGFR–PLCγ–STIM2 Cascade
por: Huang, Tzu-Yu, et al.
Publicado: (2018)

Interplay between ER Ca(2+) Binding Proteins, STIM1 and STIM2, Is Required for Store-Operated Ca(2+) Entry
por: Nelson, Heather A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3g0jq0k5dg1sgtodmdkd0qi5tq