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In vivo dual RNA-seq reveals that neutrophil recruitment underlies differential tissue tropism of Streptococcus pneumoniae

Streptococcus pneumoniae is a genetically diverse human-adapted pathogen commonly carried asymptomatically in the nasopharynx. We have recently shown that a single nucleotide polymorphism (SNP) in the raffinose pathway regulatory gene rafR accounts for a difference in the capacity of clonally-relate...

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Detalles Bibliográficos
Autores principales: Minhas, Vikrant, Aprianto, Rieza, McAllister, Lauren J., Wang, Hui, David, Shannon C., McLean, Kimberley T., Comerford, Iain, McColl, Shaun R., Paton, James C., Veening, Jan-Willem, Trappetti, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275033/
https://www.ncbi.nlm.nih.gov/pubmed/32504007
http://dx.doi.org/10.1038/s42003-020-1018-x