MutSpot: detection of non-coding mutation hotspots in cancer genomes

Recurrence and clustering of somatic mutations (hotspots) in cancer genomes may indicate positive selection and involvement in tumorigenesis. MutSpot performs genome-wide inference of mutation hotspots in non-coding and regulatory DNA of cancer genomes. MutSpot performs feature selection across hund...

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Detalles Bibliográficos
Autores principales: Guo, Yu Amanda, Chang, Mei Mei, Skanderup, Anders Jacobsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275039/
https://www.ncbi.nlm.nih.gov/pubmed/32550006
http://dx.doi.org/10.1038/s41525-020-0133-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275039/
https://www.ncbi.nlm.nih.gov/pubmed/32550006
http://dx.doi.org/10.1038/s41525-020-0133-4

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