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MutSpot: detection of non-coding mutation hotspots in cancer genomes

Recurrence and clustering of somatic mutations (hotspots) in cancer genomes may indicate positive selection and involvement in tumorigenesis. MutSpot performs genome-wide inference of mutation hotspots in non-coding and regulatory DNA of cancer genomes. MutSpot performs feature selection across hund...

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Detalles Bibliográficos
Autores principales:	Guo, Yu Amanda, Chang, Mei Mei, Skanderup, Anders Jacobsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275039/ https://www.ncbi.nlm.nih.gov/pubmed/32550006 http://dx.doi.org/10.1038/s41525-020-0133-4

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