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Combining proteogenomics and metaproteomics for deep taxonomic and functional characterization of microbiomes from a non-sequenced host

Metaproteomics of gut microbiomes from animal hosts lacking a reference genome is challenging. Here we describe a strategy combining high-resolution metaproteomics and host RNA sequencing (RNA-seq) with generalist database searching to survey the digestive tract of Gammarus fossarum, a small crustac...

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Detalles Bibliográficos
Autores principales: Gouveia, Duarte, Pible, Olivier, Culotta, Karen, Jouffret, Virginie, Geffard, Olivier, Chaumot, Arnaud, Degli-Esposti, Davide, Armengaud, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275042/
https://www.ncbi.nlm.nih.gov/pubmed/32504001
http://dx.doi.org/10.1038/s41522-020-0133-2