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Visualizing group II intron dynamics between the first and second steps of splicing

Group II introns are ubiquitous self-splicing ribozymes and retrotransposable elements evolutionarily and chemically related to the eukaryotic spliceosome, with potential applications as gene-editing tools. Recent biochemical and structural data have captured the intron in multiple conformations at...

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Detalles Bibliográficos
Autores principales: Manigrasso, Jacopo, Chillón, Isabel, Genna, Vito, Vidossich, Pietro, Somarowthu, Srinivas, Pyle, Anna Marie, De Vivo, Marco, Marcia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275048/
https://www.ncbi.nlm.nih.gov/pubmed/32503992
http://dx.doi.org/10.1038/s41467-020-16741-4