Multi-trait analysis of rare-variant association summary statistics using MTAR

Integrating association evidence across multiple traits can improve the power of gene discovery and reveal pleiotropy. Most multi-trait analysis methods focus on individual common variants in genome-wide association studies. Here, we introduce multi-trait analysis of rare-variant associations (MTAR)...

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Detalles Bibliográficos
Autores principales: Luo, Lan, Shen, Judong, Zhang, Hong, Chhibber, Aparna, Mehrotra, Devan V., Tang, Zheng-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275056/
https://www.ncbi.nlm.nih.gov/pubmed/32503972
http://dx.doi.org/10.1038/s41467-020-16591-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275056/
https://www.ncbi.nlm.nih.gov/pubmed/32503972
http://dx.doi.org/10.1038/s41467-020-16591-0

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