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Multi-trait analysis of rare-variant association summary statistics using MTAR
Integrating association evidence across multiple traits can improve the power of gene discovery and reveal pleiotropy. Most multi-trait analysis methods focus on individual common variants in genome-wide association studies. Here, we introduce multi-trait analysis of rare-variant associations (MTAR)...
Autores principales: | Luo, Lan, Shen, Judong, Zhang, Hong, Chhibber, Aparna, Mehrotra, Devan V., Tang, Zheng-Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275056/ https://www.ncbi.nlm.nih.gov/pubmed/32503972 http://dx.doi.org/10.1038/s41467-020-16591-0 |
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