Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice

Brain aging proceeds with cellular and molecular changes in the limbic system. Aging-dependent changes might affect emotion and stress coping, yet the underlying mechanisms remain unclear. Here, we show aged (18-month-old) mice exhibit upregulation of NADPH oxidase and oxidative stress in the hippoc...

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Detalles Bibliográficos
Autores principales: Lee, Jung-Eun, Kwon, Hye-Jin, Choi, Juli, Seo, Ji-Seon, Han, Pyung-Lim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275057/
https://www.ncbi.nlm.nih.gov/pubmed/32504071
http://dx.doi.org/10.1038/s42003-020-1010-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275057/
https://www.ncbi.nlm.nih.gov/pubmed/32504071
http://dx.doi.org/10.1038/s42003-020-1010-5

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