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Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice
Brain aging proceeds with cellular and molecular changes in the limbic system. Aging-dependent changes might affect emotion and stress coping, yet the underlying mechanisms remain unclear. Here, we show aged (18-month-old) mice exhibit upregulation of NADPH oxidase and oxidative stress in the hippoc...
Autores principales: | Lee, Jung-Eun, Kwon, Hye-Jin, Choi, Juli, Seo, Ji-Seon, Han, Pyung-Lim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275057/ https://www.ncbi.nlm.nih.gov/pubmed/32504071 http://dx.doi.org/10.1038/s42003-020-1010-5 |
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