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Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation

The browning of white adipose tissue (WAT) has got much attention for its potential beneficial effects on metabolic disorders, however, the nutritional factors and neuronal signals involved remain largely unknown. We sought to investigate whether WAT browning is stimulated by leucine deprivation, an...

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Detalles Bibliográficos
Autores principales: Yuan, Feixiang, Jiang, Haizhou, Yin, Hanrui, Jiang, Xiaoxue, Jiao, Fuxin, Chen, Shanghai, Ying, Hao, Chen, Yan, Zhai, Qiwei, Guo, Feifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275074/
https://www.ncbi.nlm.nih.gov/pubmed/32504036
http://dx.doi.org/10.1038/s41467-020-16662-2