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Metformin, an AMPK Activator, Inhibits Activation of FLSs but Promotes HAPLN1 Secretion

AMP-activated protein kinase (AMPK) is essential for maintaining energy balance and has a crucial role in various inflammatory pathways. In this study, AMPK levels positively correlated with many inflammatory indexes in rheumatoid arthritis (RA) patients, especially in the affected synovium. In RA s...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Qiu, Fujuan, Yu, Beijia, Chen, Yanjuan, Zuo, Fangfang, Zhu, XiaoYu, Nandakumar, Kutty Selva, Xiao, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275116/
https://www.ncbi.nlm.nih.gov/pubmed/32518807
http://dx.doi.org/10.1016/j.omtm.2020.05.008