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Metformin, an AMPK Activator, Inhibits Activation of FLSs but Promotes HAPLN1 Secretion
AMP-activated protein kinase (AMPK) is essential for maintaining energy balance and has a crucial role in various inflammatory pathways. In this study, AMPK levels positively correlated with many inflammatory indexes in rheumatoid arthritis (RA) patients, especially in the affected synovium. In RA s...
Autores principales: | Chen, Yong, Qiu, Fujuan, Yu, Beijia, Chen, Yanjuan, Zuo, Fangfang, Zhu, XiaoYu, Nandakumar, Kutty Selva, Xiao, Changhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275116/ https://www.ncbi.nlm.nih.gov/pubmed/32518807 http://dx.doi.org/10.1016/j.omtm.2020.05.008 |
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