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Estrogen-ERα signaling and DNA hypomethylation co-regulate expression of stem cell protein PIWIL1 in ERα-positive endometrial cancer cells

BACKGROUND: We previously identified PIWIL1 as an oncogene involved in endometrial carcinogenesis. However, the mechanism of Piwil1 mediated regulation of tumorigenesis remains poorly understood. METHODS: The expression levels of target genes in endometrial cancer cells were detected by quantitative...

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Detalles Bibliográficos
Autores principales: Chen, Zheng, Yang, Hua-Jing, Lin, Qin, Zhu, Min-Jiao, Yu, Ying-Ying, He, Xiao-Ying, Wan, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275358/
https://www.ncbi.nlm.nih.gov/pubmed/32503542
http://dx.doi.org/10.1186/s12964-020-00563-4