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Utility of plasma Neurofilament light as a diagnostic and prognostic biomarker of the postural instability gait disorder motor subtype in early Parkinson’s disease

BACKGROUND: The main motor subtypes of Parkinson’s disease (PD) include tremor-dominant (TD) and postural instability gait disorder (PIGD), with varying disease course that warrant the development of biomarkers capable of predicting progression according to motor subtype. The PIGD subtype is associa...

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Detalles Bibliográficos
Autores principales: Ng, Adeline Su Lyn, Tan, Yi Jayne, Yong, Alisa Cui Wen, Saffari, Seyed Ehsan, Lu, Zhonghao, Ng, Ebonne Yulin, Ng, Samuel Yong Ern, Chia, Nicole Shuang Yu, Choi, Xinyi, Heng, Dede, Neo, Shermyn, Xu, Zheyu, Keong, Nicole Chwee Har, Tay, Kay Yaw, Au, Wing Lok, Tan, Louis Chew Seng, Tan, Eng-King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275464/
https://www.ncbi.nlm.nih.gov/pubmed/32503574
http://dx.doi.org/10.1186/s13024-020-00385-5