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The initial engraftment of tumor cells is critical for the future growth pattern: a mathematical study based on simulations and animal experiments

BACKGROUND: Xenograft mouse tumor models are used to study mechanisms of tumor growth and metastasis formation and to investigate the efficacy of different therapeutic interventions. After injection the engrafted cells form a local tumor nodule. Following an initial lag period of several days, the s...

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Detalles Bibliográficos
Autores principales: Hoffmann, Bertin, Lange, Tobias, Labitzky, Vera, Riecken, Kristoffer, Wree, Andreas, Schumacher, Udo, Wedemann, Gero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275472/
https://www.ncbi.nlm.nih.gov/pubmed/32503458
http://dx.doi.org/10.1186/s12885-020-07015-9