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The initial engraftment of tumor cells is critical for the future growth pattern: a mathematical study based on simulations and animal experiments
BACKGROUND: Xenograft mouse tumor models are used to study mechanisms of tumor growth and metastasis formation and to investigate the efficacy of different therapeutic interventions. After injection the engrafted cells form a local tumor nodule. Following an initial lag period of several days, the s...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275472/ https://www.ncbi.nlm.nih.gov/pubmed/32503458 http://dx.doi.org/10.1186/s12885-020-07015-9 |