Ezh2-mediated epigenetic modification is required for allogeneic T cell-induced lupus disease

BACKGROUND: The mechanisms involved in the pathogenesis of autoimmune disorders, including systemic lupus erythematosus (SLE), have not been fully elucidated. Some of these mechanisms involve epigenetic regulation of gene expression. The histone methyltransferase Ezh2 contributes to epigenetic regul...

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Detalles Bibliográficos
Autores principales: Zhen, Yuxuan, Smith, Roger D., Finkelman, Fred D., Shao, Wen-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275547/
https://www.ncbi.nlm.nih.gov/pubmed/32503684
http://dx.doi.org/10.1186/s13075-020-02225-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275547/
https://www.ncbi.nlm.nih.gov/pubmed/32503684
http://dx.doi.org/10.1186/s13075-020-02225-9

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