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Ezh2-mediated epigenetic modification is required for allogeneic T cell-induced lupus disease
BACKGROUND: The mechanisms involved in the pathogenesis of autoimmune disorders, including systemic lupus erythematosus (SLE), have not been fully elucidated. Some of these mechanisms involve epigenetic regulation of gene expression. The histone methyltransferase Ezh2 contributes to epigenetic regul...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275547/ https://www.ncbi.nlm.nih.gov/pubmed/32503684 http://dx.doi.org/10.1186/s13075-020-02225-9 |