The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells

OBJECTIVE: Patients with systemic lupus erythematosus (SLE) have an ongoing interferon (IFN) production due to an activation of plasmacytoid dendritic cells (pDCs), which can be triggered to type I IFN synthesis by RNA containing immune complexes (RNA-IC). Considering emerging data suggesting a role...

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Detalles Bibliográficos
Autores principales: Hjorton, Karin, Hagberg, Niklas, Pucholt, Pascal, Eloranta, Maija-Leena, Rönnblom, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275601/
https://www.ncbi.nlm.nih.gov/pubmed/32503683
http://dx.doi.org/10.1186/s13075-020-02186-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275601/
https://www.ncbi.nlm.nih.gov/pubmed/32503683
http://dx.doi.org/10.1186/s13075-020-02186-z

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