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Sex differences in pharmacokinetics predict adverse drug reactions in women

BACKGROUND: Women experience adverse drug reactions, ADRs, nearly twice as often as men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood. Most drugs currently in use were approved based on clinical trials conducted on men, so women may be overmedicated. We d...

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Detalles Bibliográficos
Autores principales: Zucker, Irving, Prendergast, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275616/
https://www.ncbi.nlm.nih.gov/pubmed/32503637
http://dx.doi.org/10.1186/s13293-020-00308-5