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Sirtuin (Sirt) 3 Overexpression Prevents Retinopathy in Streptozotocin-Induced Diabetic Rats

BACKGROUND: Sirtuin (Sirt) 3 could promote autophagy by downregulating the expression of genes related to neovascularization in retinal endothelial cells. In this study, we aimed to investigate the effect of Sirt3 overexpression on retinopathy in streptozotocin (STZ)-induced diabetic rats, and to as...

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Detalles Bibliográficos
Autores principales: Mao, Xin-bang, Cheng, Yan-hua, Peng, Ke-su, You, Zhi-peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275642/
https://www.ncbi.nlm.nih.gov/pubmed/32506069
http://dx.doi.org/10.12659/MSM.920883