Cargando…
Marginal zone SIGN-R1(+) macrophages are essential for the maturation of germinal center B cells in the spleen
The mechanisms that regulate germinal center (GC) B cell responses in the spleen are not fully understood. Here we use a combination of pharmacologic and genetic approaches to delete SIGN-R1(+) marginal zone (MZ) macrophages and reveal their specific contribution to the regulation of humoral immunit...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275705/ https://www.ncbi.nlm.nih.gov/pubmed/32424104 http://dx.doi.org/10.1073/pnas.1921673117 |