Cargando…
Marginal zone SIGN-R1(+) macrophages are essential for the maturation of germinal center B cells in the spleen
The mechanisms that regulate germinal center (GC) B cell responses in the spleen are not fully understood. Here we use a combination of pharmacologic and genetic approaches to delete SIGN-R1(+) marginal zone (MZ) macrophages and reveal their specific contribution to the regulation of humoral immunit...
Autores principales: | Pirgova, Gabriela, Chauveau, Anne, MacLean, Andrew J., Cyster, Jason G., Arnon, Tal I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275705/ https://www.ncbi.nlm.nih.gov/pubmed/32424104 http://dx.doi.org/10.1073/pnas.1921673117 |
Ejemplares similares
-
Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones
por: Chauveau, Anne, et al.
Publicado: (2020) -
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone
por: Muppidi, Jagan R., et al.
Publicado: (2011) -
Visualization of splenic marginal zone B cell shuttling and follicular B cell egress
por: Arnon, Tal I., et al.
Publicado: (2012) -
New Insights into the Cell Biology of the Marginal Zone of the Spleen
por: Kraal, Georg, et al.
Publicado: (2006) -
Rituximab in the Treatment of Acquired Angioedema Secondary to Marginal Zone Lymphoma of the Spleen
por: Wu, Kathie, et al.
Publicado: (2023)