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Functional stability of water wire–carbonyl interactions in an ion channel

Water wires are critical for the functioning of many membrane proteins, as in channels that conduct water, protons, and other ions. Here, in liquid crystalline lipid bilayers under symmetric environmental conditions, the selective hydrogen bonding interactions between eight waters comprising a water...

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Detalles Bibliográficos
Autores principales: Paulino, Joana, Yi, Myunggi, Hung, Ivan, Gan, Zhehong, Wang, Xiaoling, Chekmenev, Eduard Y., Zhou, Huan-Xiang, Cross, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275723/
https://www.ncbi.nlm.nih.gov/pubmed/32414918
http://dx.doi.org/10.1073/pnas.2001083117