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Host nutrient milieu drives an essential role for aspartate biosynthesis during invasive Staphylococcus aureus infection

The bacterial pathogen Staphylococcus aureus is capable of infecting a broad spectrum of host tissues, in part due to flexibility of metabolic programs. S. aureus, like all organisms, requires essential biosynthetic intermediates to synthesize macromolecules. We therefore sought to determine the met...

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Detalles Bibliográficos
Autores principales: Potter, Aimee D., Butrico, Casey E., Ford, Caleb A., Curry, Jacob M., Trenary, Irina A., Tummarakota, Srivarun S., Hendrix, Andrew S., Young, Jamey D., Cassat, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275739/
https://www.ncbi.nlm.nih.gov/pubmed/32414924
http://dx.doi.org/10.1073/pnas.1922211117