Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice

Purpose: Overexpression of epithelial cell adhesion molecule (EpCAM) correlates with poor prognosis, therapeutic failure and early tumor recurrence in hepatocellular carcinoma (HCC) patients. The tumor microenvironment dictates the fate of tumor-initiating cancer stem cells (CSCs); however, very lim...

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Detalles Bibliográficos
Autores principales: Pandit, Harshul, Li, Yan, Zheng, Qianqian, Guo, Wei, Yu, Youxi, Li, Suping, Martin, Robert C.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275786/
https://www.ncbi.nlm.nih.gov/pubmed/32547703
http://dx.doi.org/10.18632/oncotarget.27454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275786/
https://www.ncbi.nlm.nih.gov/pubmed/32547703
http://dx.doi.org/10.18632/oncotarget.27454

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