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Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice
Purpose: Overexpression of epithelial cell adhesion molecule (EpCAM) correlates with poor prognosis, therapeutic failure and early tumor recurrence in hepatocellular carcinoma (HCC) patients. The tumor microenvironment dictates the fate of tumor-initiating cancer stem cells (CSCs); however, very lim...
Autores principales: | Pandit, Harshul, Li, Yan, Zheng, Qianqian, Guo, Wei, Yu, Youxi, Li, Suping, Martin, Robert C.G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275786/ https://www.ncbi.nlm.nih.gov/pubmed/32547703 http://dx.doi.org/10.18632/oncotarget.27454 |
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