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The Effects of WW2/WW3 Domains of Smurf2 Molecule on CD4(+)CD25(+)/CD4(+) Proportion in Spleen of 4T1 Tumor Bearing BALB/c Mice
BACKGROUND: TGF-β has long been considered as the main inducer of Tregs in tumor microenvironment and is the reason for the aberrant number of Tregs in tumor-bearing individuals. Recently, it has been suggested that the enzyme arginase I is able to mediate the induction of Tregs in a TGF-β-independe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Pasteur Institute of Iran
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275819/ https://www.ncbi.nlm.nih.gov/pubmed/32306719 http://dx.doi.org/10.29252/ibj.24.4.214 |